Once youve assessed tolerance and effect, you may increase your dose in a stepwise fashion. This will help you choose the right product. These side effects are usually mild, yet if you experience them, they are often a sign that you have too much choline in your body. The way you take Alpha-GPC for cognitive enhancement will depend on your goals. Two common types are CDP-Choline (Citicoline) and Choline Bitartrate / Lecithin. How Do You Take Alpha-GPC For Cognitive Enhancement? Heres an example of an alpha GPC stack that includes the popular nootropic Noopept and a racetam, aniracetam. Unbiased Metabolite Profiling of Schizophrenia Fibroblasts under Stressful Perturbations Reveals Dysregulation of Plasmalogens and Phosphatidylcholines. However, it is banned by some athletic organizations. First, make sure you're buying from a reputable source. Choline bitartrate, while cheaper, does not raise neural Choline levels. See our medical disclaimer. Alpha GPC is naturally present in the body in small amounts, and it is also commercially manufactured as a supplement using purified soy lecithin. There have been numerous studies conducted which speak to the effectiveness of Alpha GPC in achieving the benefits examined above. This is significant to focus because dopamine is "motivation" at a chemical level. In clinical studies, alpha-GPC dosage ranged from 250 to 1,200mg/day. Should you stack Huperzine A and Alpha-GPC? Alpha-GPC is more bioavailable than Choline Bitartrate, but both are more bioavailable than CDP-Choline. The focus of this article is on helping you decide whether Alpha-GPC is a substance that you should consider adding to your diet, or to your existing supplement routine. Acute supplementation with alpha-glycerylphosphorylcholine augments growth hormone response to, and peak force production during, resistance exercise. Alpha-GPC is considered GRAS (Generally Recognized As Safe) by the FDA. Alpha-GPC's half-life is 4-6 hours. Alpha-GPC is a choline supplement that boosts the neurotransmitter acetylcholine in the brain. Alpha GPC is generally well tolerated when taken at recommended dosages. Other studies have suggested that Alpha GPC can improve memory formation as well as learning ability. NooCube is our top-rated cognitive enhancer, and it contains a range of powerful nootropics that work together to enhance cognitive function. View abstract. CDP Choline also breaks down into Uridine: This is the reason why Citicoline is only 18.5% Choline by weight. [8] The No Observed Adverse Effect Level is 150 mg per kg of body weight per day. The multiple administrations are important in order to combat the fact that Piracetam has a very short 2 or three hour half-life. Executive function means our ability to plan, organize and manage time. 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Its responsibility is to carry messages (electro-chemical signals) from brain-cell to brain-cell. Alpha-GPC has a half life of 4-6 hours, so many people choose to take it at multiple [points throughout the day to supplement their choline levels. It is best to aim for a ratio of between 4:1 and 8:1 in favor of Piracetam. It is also prescribed to treat memory loss and cognition impairment related to stroke, traumatic brain injury, and dementia.[3], Though most research has focused on age-related memory loss, alpha GPCs memory benefits dont seem limited to the elderly. If you're looking for a cognitive boost, we recommend taking Alpha-GPC around half an hour before you need to be at your best. Things that require the use of our frontal cortex (the large area at the front of our brains). The finer details and scientific reasoning behind this: 1. Though no overdoses have been documented, adverse side effects are more commonly reported among users taking high dosages. 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